2023

Modeling and Remodeling the Cell: How Digital Twins and HCMV Can Elucidate the Complex Interactions of Viral Latency, Epigenetic Regulation, and Immune Responses. Current Clinical Microbiology Reports. DOI: 10.1007/s40588-023-00201-w

Hana McMahon-Cole, Alicia Johnson, Sara Sadat Aghamiri, Tomas Helikar, and Lindsey B. Crawford

Hematopoietic stem cells and betaherpesvirus latency. Frontiers in Cellular and Infection Microbiology. DOI: 10.3389/fcimb.2023.1189805

Lindsey B. Crawford

2022

Human Embryonic Stem Cells as a Model for Hematopoietic Stem Cell Differentiation and Viral Infection. Current Protocols. DOI: 10.1002/cpz1.622

Lindsey B. Crawford

Advances in Model Systems for Human Cytomegalovirus Latency and Reactivation. mBio. DOI: 10.1128/mbio.01724-21

Lindsey B. Crawford, Nicole L. Diggins, Patrizia Caposio, and Meaghan H. Hancock.

2021

CD34+ Hematopoietic Progenitor Cell Subsets Exhibit Differential Ability to Maintain Human Cytomegalovirus Latency and Persistence. Journal of Virology. 

Lindsey B. Crawford, Meaghan H. Hancock, Hillary M. Struthers, Daniel N. Streblow, Andrew D. Yurochko, Patrizia Caposio, Felicia D. Goodrum, and Jay A. Nelson.

Human Cytomegalovirus miR-US25-1 Targets the GTPase RhoA to Inhibit CD34+ Hematopoietic Progenitor Cell Proliferation to Maintain the Latent Viral Genome. mBio. 

Nicole L. Diggins, Lindsey B. Crawford, Meaghan H. Hancock, Jennifer Mitchell, and Jay A. Nelson

Human Cytomegalovirus UL7, miR-US5-1 and miR-UL112-3p Inactivation of FOXO3 Protects CD34+ Hematopoietic Progenitor Cells from Apoptosis. mSphere.

Meaghan H. Hancock, Lindsey B. Crawford, Wilma Perez, Hillary M. Struthers, Jennifer Mitchell, and Patrizia Caposio.

2020

Human Cytomegalovirus Infection Suppresses CD34+ Progenitor Cell Engraftment in Humanized Mice. Microorganisms. 

 Lindsey B. Crawford, Rebecca Tempel, Daniel N. Streblow, Andrew D. Yurochko, Felicia D. Goodrum, Jay A. Nelson, and Patrizia Caposio. 

Human Cytomegalovirus miRNAs Regulate TGF-B to Mediate Myelosuppression while Maintaining Viral Latency in CD34+ Hematopoietic Progenitor Cells. Cell Host and Microbe. 

Meaghan H. Hancock* and Lindsey B. Crawford*, Andrew H. Pham, Jennifer Mitchell, Hillary M. Struthers, Andrew D. Yurochko, Patrizia Caposio, and Jay A. Nelson

Spatial and biochemical interactions between bone marrow adipose tissue and hematopoietic stem and progenitor cells. Bone.

Jacob J. Robino, Nathalie Parmir, Sara Rosario, Lindsey B. Crawford, Benjamin J. Burwitz, Charles T. Roberts Jr, Peter Kurre, and Oleg Varlamov